SUMO2/3 MODIFICATION OF TRANSCRIPTION-ASSOCIATED PROTEINS CONTROLS CELL VIABILITY IN RESPONSE TO OXYGEN AND GLUCOSE DEPRIVATION-MEDIATED STRESS

SUMO2/3 modification of transcription-associated proteins controls cell viability in response to oxygen and glucose deprivation-mediated stress

Abstract Because limited oxygen and glucose supply to tissues is a serious challenge that cells must properly measure to decide between surviving or triggering cell death, organisms have developed accurate mechanisms for sensing and signaling these conditions.In recent years, signaling through posttranslational modification of proteins by covalent

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Taste bud formation depends on taste nerves

It has been known for more than a century that, MINI CHOC CHIPS in adult vertebrates, the maintenance of taste buds depends on their afferent nerves.However, the initial formation of taste buds is proposed to be nerve-independent in amphibians, and evidence to the contrary in mammals has been endlessly debated, mostly due to indirect and incomplete

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Similarly Torn, Differentially Shorn? The Experience and Management of Conflict between Multiple Roles, Relationships, and Social Categories

In three studies we examined the experience and Cocktail Shakers management of conflict between different types of multiple identities.Participants described a conflict between pairs of role, relational, or social identities before rating the experience (i.e., magnitude, stress, and growth) and management of conflict on a newly developed scale asse

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Research of IGBT Module Application Failure for Locomotive

Aiming at the problem of explosion damage of IGBT module used in locomotive after bottoms application failure, which makes it difficult to find the failure reason.The switch state of IGBT module under the application condition was analyzed, and five failure modes were put forward.Based on the statistical distribution of failure modes in the factory

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Swarm shedding in networks of self-propelled agents

Abstract Understanding swarm pattern formation is of great interest because it occurs naturally in many physical and biological systems, and has artificial applications in robotics.In both natural and engineered swarms, agent communication is typically local and sparse.This tactical umbrella is because, over a limited sensing or communication range

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